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KMID : 1164219970090010106
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Journal of Korean Society for Radiotherapeutic Technology
1997 Volume.9 No. 1 p.106 ~ p.112
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The Effects of MDCK Cell on Low Dose Irradiation
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Lee Song-Jae
Jang Jae-Chul
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Abstract
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The present study was undertaken to investigate the effects of cultured MDCK cell line on the cell viability and the activities of superoxide dismutase(SOD). catalase, change of FOX 1 with low dose radiation. When MDCK cells were irradiated low dose (less than 50 cGy), the cell viability remains high after 2 hrs, but few changes after 24 hrs. In the low dose irradiated MDCK cells, the activities of SOD and catalase were increased with compared to control group and high dose. But the content of (FOX 1) was decreased. These results suggest that the cultured MDCK cells probably were induced expression of defense mechanism.
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KEYWORD
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